Provide Top High Quality 100% Natural Reasonable Price Mollugin CAS NO.:55481-88-4

Product Properties

Provide top High Quality 100% Natural Reasonable Price Mollugin CAS NO.:55481-88-4

Product Name: Mollugin

CAS NO.: 55481-88-4

_{MF: C17H16O4}
Appearance:white powder
Detection Method: HPLC
Purity: 99%
EINECS NO.: 55481-88-4

Shaanxi Baisfu Bioengineering Co., Ltd. is an enterprise specializing in the research and development, production and sales of flavors and fragrances. The company is located in Building A, Baodeyun Valley, No. 52, Jinye 1st Road, Yanta District, Xi'an City, Shaanxi Province. It has an excellent geographical location and convenient transportation. convenient. The company was established in December 2019, with a registered capital of 3 million yuan.

The company's main products include cooling agents, synthetic flavors and natural flavors. The company's products can be used in food and beverage, daily chemical, and other industries, and have a wide range of downstream applications.

The company always attaches great importance to product quality and brand reputation, strictly implements product quality and environmental management control, and has passed various certifications such as GPM, ISO9001, ISO14001, kosher, and HALAL European analysis.

The company's products are used by more than 30 foreign companies and regions. After more than ten years of technology accumulation and market development, the company has accumulated a group of high-quality customer groups, stable customer channels and resources, and has established relationships with more than 100 domestic and foreign companies. Good working relations.

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Packing & Delivery

Mollugin
CAS NO.:55481-88-4

Package: 125ml Sample Package; 1L Standard Package;500ml,1L/Bottle; 5L,10L/Drum; 15L,20L/Carton; or according to customers' requirement.
Storage: Store in cool & dry place. Keep away from strong light and heat.

Delivery: 1-2 working days after payment/FedEx, DHL, TNT, EMS, etc.

Detailed Description

Mollugin
CAS NO.:55481-88-4

Mollugin, a bioactive phytochemical isolated from Rubia cordifolia L., has shown preclinical anticancer efficacy in various cancer models. However the effects of mollugin in regulating cancer cell survival and death remains undefined. In the present study we found that mollugin exhibited cytotoxicity on various cancer models. The suppression of cell viability was due to the induction of mitochondria apoptosis. In addition, the presence of autophagic hallmarks was observed in mollugin-treated cells. Notably, blockade of autophagy by a chemical inhibitor or RNA interference enhanced the cytotoxicity of mollugin. Further experiments demonstrated that phosphatidylinositide 3-kinases/protein kinase B/mammalian target of rapamycin/p70S6 kinase (PI3K/AKT/mTOR/p70S6K) and extracellular regulated protein kinases (ERK) signaling pathways participated in mollugin-induced autophagy and apoptosis. Together, these findings support further studies of mollugin as candidate for treatment of human cancer cells.

Function

Mollugin
CAS NO.:55481-88-4

Mollugin exhibits cytotoxicity and activates autophagy in cancer models.

Mollugin induces mitochondrial apoptosis in glioblastoma cells.

Inhibition of autophagy enhances apoptosis.

Mollugin inhibits PI3K/AKT/mTOR/p70S6K signaling pathway.

Mollugin inhibits ERK signaling pathway.

Application

Mollugin
CAS NO.:55481-88-4

Mollugin Apoptosis Autophagy PI3K/AKT/mTOR/p70S6K ERK

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