Baisfu High Quality Top Grade Wholesale White Powder Phillygenin, Hot Sell 98% Phillygenin Cas. 487-39-8

Product Properties

Baisfu High Quality Top Grade Wholesale White Powder Phillygenin, Hot Sell 98% Phillygenin Cas. 487-39-8

Product Name: Phillygenin
CAS.: 487-39-8
MF: C29H36O15

MW: 624.5871

Appearance: white Powder
Detection Method: HPLC
Purity: 98%

Shelf life: 2Years

Shaanxi Baisfu Bioengineering Co., Ltd. is an enterprise specializing in the research and development, production and sales of flavors and fragrances. The company is located in Building A, Baodeyun Valley, No. 52, Jinye 1st Road, Yanta District, Xi'an City, Shaanxi Province. It has an excellent geographical location and convenient transportation. convenient. The company was established in December 2019, with a registered capital of 3 million yuan.

The company's main products include cooling agents, synthetic flavors and natural flavors. The company's products can be used in food and beverage, daily chemical, and other industries, and have a wide range of downstream applications.

The company always attaches great importance to product quality and brand reputation, strictly implements product quality and environmental management control, and has passed various certifications such as GPM, ISO9001, ISO14001, kosher, and HALAL European analysis.

The company's products are used by more than 30 foreign companies and regions. After more than ten years of technology accumulation and market development, the company has accumulated a group of high-quality customer groups, stable customer channels and resources, and has established relationships with more than 100 domestic and foreign companies. Good working relations.

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Packing & Delivery

Baisfu High Quality Top Grade Wholesale White Powder Phillygenin, Hot Sell 98% Phillygenin Cas. 487-39-8

Package: 1kg per bag with double plastic inside and aluminium foil bag outside, or 25kg per fibre drum with double plastic bag inside, or according to customers' requirement.
Storage: Store in cool & dry place. Keep away from strong light and heat.

Delivery: 1-2 working days after payment/FedEx, DHL, TNT, EMS, etc.

Detailed Description

Baisfu High Quality Top Grade Wholesale White Powder Phillygenin, Hot Sell 98% Phillygenin Cas. 487-39-8

Product Name: Phillygenin
CAS.: 487-39-8
MF: C29H36O15
MW: 624.5871
Appearance: white Powder
Detection Method: HPLC
Purity: 98%
Shelf life: 2Years

Functions

Baisfu High Quality Top Grade Wholesale White Powder Phillygenin, Hot Sell 98% Phillygenin Cas. 487-39-8

​Inflammation is a common pathological phenomenon when homeostasis is seriously disturbed. Phillygenin (PHI), a lignin component isolated from Forsythiae Fructus, has shown a good anti-inflammatory effect. However, the mechanisms of PHI on anti-inflammation have not yet been systematically elucidated. In this study, the lipopolysaccharide (LPS) - induced RAW264.7 cell inflammation model was established to investigate mechanisms of PHI on inflammation. The effect of PHI on the release of IL-1β and PGE2 inflammatory factors induced by LPS was detected by ELISA, and the mRNA expressions of IL-1β, IL-6 and TNF-α were detected by RT-qPCR. Proteomics studied the signaling pathways that might be affected by PHI and molecular docking technology was subsequently used to study the possible targets on proteomic screened pathways. Western blot was performed ultimately to detect progressive changes in protein expression on the related pathway. Our research showed that PHI significantly inhibited the robust increase of IL-1β and PGE2 and lowered the transcriptional level of inflammatory genes including IL-6, IL-1β and PGE2 in LPS-stimulated RAW264.7 cells. Proteomics results indicated that PHI was involved in the regulation of multiple signaling pathways. Molecular docking results indicated that PHI had an affinity for most proteins in NF-κB pathway. Western blot analysis proved that PHI inhibited LPS-induced NF-κB pathway activation. On the whole, PHI inhibited the activation of NF-κB pathway, thereby inhibiting the expression of related inflammatory genes and the release of cytokines, and showed a remarkable anti-inflammatory effect.

How to Order

1. Make sure your quantity need and Leave us message, with your mailed details shown: Including contact name, address information, contact phone, etc.
2. We send you a PI (Proforma Invoice) for price and payment detail.
3. Payment by Paypal or Western Union or T/T.
4. We arrange the delivery and update you the tracking number in time.

FAQ

Q1:Can I get some samples?

A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: How do I order and pay?

A: Proforma invoice will be sent after confirmation of order. Payment by T/T, Western Union or Paypal.

Q3: Can you accept small order?

A:Yes.

Q4: How about delivery leadtime?

A: About 3-6 days after payment confirmed. (Except Chinese holiday)

Q5: How to confirm the Product Quality before placing orders?

A: You can get free samples for your testing.We can manufacture the products according to your specific requirment.

Q6: ls there a discount?

A: Different quantity has different discount