Baisfu White Powder High Quality 100% Natural 3-Indoleformic Acid3-Indolecarboxylic Acid CAS NO.771-50-6

Product Properties

Baisfu White Powder High Quality 100% Natural 3-Indoleformic Acid3-Indolecarboxylic Acid CAS NO.771-50-6
CAS NO.:771-50-6

Product Name:1H-Indole-3-carboxylic acid

CAS NO.: 771-50-6

_MF:C₉H₇NO₂
Appearance:white powder
Detection Method: HPLC
Purity: 99%
EINECS NO.: 771-50-6

Shaanxi Baisfu Bioengineering Co., Ltd. is an enterprise specializing in the research and development, production and sales of flavors and fragrances. The company is located in Building A, Baodeyun Valley, No. 52, Jinye 1st Road, Yanta District, Xi'an City, Shaanxi Province. It has an excellent geographical location and convenient transportation. convenient. The company was established in December 2019, with a registered capital of 3 million yuan.

The company's main products include cooling agents, synthetic flavors and natural flavors. The company's products can be used in food and beverage, daily chemical, and other industries, and have a wide range of downstream applications.

The company always attaches great importance to product quality and brand reputation, strictly implements product quality and environmental management control, and has passed various certifications such as GPM, ISO9001, ISO14001, kosher, and HALAL European analysis.

The company's products are used by more than 30 foreign companies and regions. After more than ten years of technology accumulation and market development, the company has accumulated a group of high-quality customer groups, stable customer channels and resources, and has established relationships with more than 100 domestic and foreign companies. Good working relations.

effect
 

Packing & Delivery

Baisfu White Powder High Quality 100% Natural 3-Indoleformic Acid3-Indolecarboxylic Acid CAS NO.771-50-6

Package: 1kg per bag with double plastic inside and aluminium foil bag outside, or 25kg per fibre drum with double plastic bag inside, or according to customers' requirement.
Storage: Store in cool & dry place. Keep away from strong light and heat.

Delivery: 1-2 working days after payment/FedEx, DHL, TNT, EMS, etc.

Detailed Description

Baisfu White Powder High Quality 100% Natural 3-Indoleformic Acid3-Indolecarboxylic Acid CAS NO.771-50-6
CAS NO.:771-50-6

In preclinical studies, the behavioral effects of serotonin antagonists at 5-HT3 receptor sites suggest potential efficacy in the treatment of anxiety and schizophrenia. The present study shows that 5-HT3 antagonists were effective in disinhibiting behavior in non-conditioned rodent models which elicit a behavioral state presumed to be analogous to anxiety, but were generally not effective in conditioned rodent anxiety models or in assays that are traditionally predictive of antipsychotic agents. Ondansetron (0.01–0.1 mg/kg), zacopride (0.1–1.0 mg/kg), ICS 205–930 (3α-tropanyl-1H-indole-3-carboxylic acid ester; 0.5 and 1.0 mg/kg), and MDL 72222 (1αH, 3α, 5αH-tropan-3-yl-3,5-dichlorobenzoate; 10.0 and 20.0 mg/kg) demonstrated anxiolytic effects in the social interaction and elevated plus maze procedures, while having little or no effect in a modified Cook and Davidson conflict procedure. Ondansetron, zacopride, and ICS 205–930 had no effect in neuroleptic screening procedures, such as the apomorphine climbing mouse assay (CMA), the pole climb avoidance (PCA) procedure, and the intracranial self-stimulation of the medial forebrain bundle (ICSS-MFB) assay. MDL 72222 had no effect on CMA but dose-dependently antagonized PCA (ED50 = 10.9 mg/kg) and ICSS-MFB (ED50 = 8.8 mg/kg). The results of the present study suggest that MDL 72222 possesses a profile of activity that is different from the other 5-HT3 antagonists tested and that, in general, 5-HT3 antagonists may prove to be efficacious in the treatment of certain forms of anxiety in man.

Function

Baisfu White Powder High Quality 100% Natural 3-Indoleformic Acid3-Indolecarboxylic Acid CAS NO.771-50-6
CAS NO.:771-50-6


A series of aryl tropanyl esters and amides related to 1H-indole-3-carboxylic acid endo 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester (ICS 205930, CAS 89565-68-4) were synthesized and evaluated for antinociceptive activity using the hot-plate test. Of these, the benzofurane-3-carboxylic ester of tropine (1) was found powerfully to increase the pain threshold, with a cholinergic mechanism of action. Despite the structural similarity with ICS 205930, the analgesia induced by 1 seems not to be due to 5-HT3 receptor interaction, and there is evidence of involvement of the central 5-HT4 receptor.

How to Order

1. Make sure your quantity need and Leave us message, with your mailed details shown: Including contact name, address information, contact phone, etc.
2. We send you a PI (Proforma Invoice) for price and payment detail.
3. Payment by Paypal or Western Union or T/T.
4. We arrange the delivery and update you the tracking number in time.

FAQ

Q1: Could you provide free sample for test?
A1: We can provide you free sample for test, and you only need to pay the delivery cost.

Q2: Which payment terms do you accept?
A2: PayPal, T/T, West Union, Bank Transfer, etc.

Q3: What's about the MOQ ?
A3: It depends on different products. Usually our MOQ is 5kg.

Q4: What’s the delivery lead time?
A4: We will make delivery within 1-2 days after receiving payment.

Q5: What about the delivery port?
A5: Main ports in China are available (Hong Kong,Guangzhou,Shenzhen).