Product Properties
Manufacturers Bulk Supply Pure Natural High Quality 98% Tetramethylpyrazine/Ligustrazine/Chuanxiongzine CAS NO. 1124-11-4
2,3,5,6-Tetramethylpyrazine;
2,3,5,6-tetramethylpyrazine;
Pyrazine, tetramethyl-;
Product Name:
Tetramethylpyrazine/Ligustrazine/Chuanxiongzine
CAS NO.: 1124-11-4
MW: 136.19 MF: C8H12N2
Detection Method: HPLC Purity: 99%
Specification:
Tetramethylpyrazine/Ligustrazine/Chuanxiongzine 98%
Main Ingredients:
Tetramethylpyrazine/Ligustrazine/Chuanxiongzine
Appearance and Properties: white crystal or powder
Density: 1.08
Melting Point: 77-80 ° C (lit.)
Boiling Point: 190 ° C (lit.)
Flash Point: 128-130 ° C / 200mm
Refractive Index: 1.503
Stability: stable. Incompatible with strong acids, strong oxidizers.
Storage Conditions: Store in a closed container. Store in a cool, dry, well-ventilated area away from incompatible materials.
Vapor Pressure: 0.671 mmHg at 25 ° C
Shelf Life: Two years
Shaanxi Baisfu Bioengineering Co., Ltd. is an enterprise specializing in the research and development, production and sales of flavors and fragrances. The company is located in Building A, Baodeyun Valley, No. 52, Jinye 1st Road, Yanta District, Xi'an City, Shaanxi Province. It has an excellent geographical location and convenient transportation. convenient. The company was established in December 2019, with a registered capital of 3 million yuan.
The company's main products include cooling agents, synthetic flavors and natural flavors. The company's products can be used in food and beverage, daily chemical, and other industries, and have a wide range of downstream applications.
The company always attaches great importance to product quality and brand reputation, strictly implements product quality and environmental management control, and has passed various certifications such as GPM, ISO9001, ISO14001, kosher, and HALAL European analysis.
The company's products are used by more than 30 foreign companies and regions. After more than ten years of technology accumulation and market development, the company has accumulated a group of high-quality customer groups, stable customer channels and resources, and has established relationships with more than 100 domestic and foreign companies. Good working relations.
effect
Packing & Delivery
Package: 1kg per bag with double plastic inside and aluminium foil bag outside, or 25kg per fibre drum with double plastic bag inside, or according to customers' requirement.
Storage: Store in cool & dry place. Keep away from strong light and heat.
Delivery: 1-2 working days after payment/FedEx, DHL, TNT, EMS, etc.
Detailed Description
Manufacturers Bulk Supply Pure Natural High Quality 98% Tetramethylpyrazine/Ligustrazine/Chuanxiongzine CAS NO. 1124-11-4
2,3,5,6-Tetramethylpyrazine;
2,3,5,6-tetramethylpyrazine;
Pyrazine, tetramethyl-;
Tetramethylpyrazine/Ligustrazine/Chuanxiongzine is Colorless needle-shaped crystals, melting point 80-82 ° (microscopic determination), the boiling point of 190 °. With a special stench, hygroscopic, easy sublimation. Soluble in hot water, soluble in chloroform, dilute hydrochloric acid, insoluble in cold water.
Functions
Manufacturers Bulk Supply Pure Natural High Quality 98% Tetramethylpyrazine/Ligustrazine/Chuanxiongzine CAS NO. 1124-11-4
2,3,5,6-Tetramethylpyrazine;
2,3,5,6-tetramethylpyrazine;
Pyrazine, tetramethyl-;
Tetramethylpyrazine/Ligustrazine/Chuanxiongzine there is antagonism of adrenaline and potassium chloride induced contraction of isolated arteries in rabbits. Can significantly increase coronary flow, reduce arterial pressure and coronary resistance. Can be through the blood-brain barrier, rabbit intravenous injection of mesenteric microcirculation can be observed in the blood flow velocity and increased number of microvessels, it is to promote the role of microcirculation. Can inhibit ADP-induced rabbit platelet aggregation in vitro, when 1mg / ml, the inhibition rate of up to 94.3%. Rats intravenous injection of 60mg / kg, the venous shunt thrombosis inhibition, and the rabbit ear vein by thrombus in the thrombus caused by no inhibition, therefore, tetramethylpyrazine may inhibit platelet aggregation and prevent arterial thrombosis form. Anti-platelet function of TMPZ enhances intracellular cAMP by inducing the inhibition of intracellular Ca ++ mobilization by inhibiting phosphodiesterase activity while reducing GP IIb / IIIa exposure on activated platelets. At CPB, TMPZ maintains platelet morphology Complete and Quantitative and Functional Effects Under high shear stress, platelet thrombosis is thought to occur through the interaction of von Willebrand factor (vWF) with the platelet receptor proteins GP Iba and GP IIb / IIIa. TMPZ exerts an anti-platelet effect, probably by inhibiting vWF-mediated platelet thrombosis. In addition, detection of P-selectin surface expression and particle release by quantitative flow cytometry can be inhibited by TMPZ. TMP has a direct vasodilatory effect, and K-channel-specific blockers against KCa (small conductance calcium-activated potassium channel) or KATP (ATP-sensitive potassium channel) can block the effect of TMP. In addition, TMP-induced vasodilation can be reversed by soluble guanylate cyclase inhibitors. Similar to K-channel blockers. The results suggest that TMP-induced vasodilation is associated with the opening of SKCa and KATP channels.
Applications
Natural High Quality Tetramethylpyrazine/Ligustrazine/Chuanxiongzine Hot Selling with Factory Price CAS NO. 1124-11-4
2,3,5,6-Tetramethylpyrazine;
2,3,5,6-tetramethylpyrazine;
Pyrazine, tetramethyl-;
Used as flavoring agents, sweet enhancers for alcoholic beverages, flavors and supplements for cigarettes.
Anti-platelet aggregation, dilatation of the arterioles, improve microcirculation and cerebral blood flow. For occlusive vascular disease, cerebral thrombosis, vasculitis, coronary heart disease, angina and so on.
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FAQ
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